You can delete the selected data points by pressing Del on the keyboard, or by choosing Clear selected data from the Data menu.
You can delete the last data point in the list by pressing Ctrl+Backspace, or by choosing Delete last data point from the Data menu.
You can delete all data from the current data set by pressing Ctrl+Del, or choosing Clear current data set from the Data menu.
To keep all data within a rectangular range and delete the rest, select the range by drawing a rectangle with the right mouse button. Then press Ctrl+I to invert the selection, and press Del.
See also: Manipulating data, Selecting data points.